Engineered Genetic Systems for Rapid Evolution and Synthetic Biology

We engineer genetic systems that go beyond what nature’s genetic systems can do. We are especially interested in synthesizing living cells that dramatically accelerate the speed of evolution, that reinterpret the genetic code, and that can record transient information. We apply these cells to the discovery of useful biomolecules, biopolymers, and therapeutics, the study of molecular evolution, gene therapy, and the creation of synthetic life. Our research spans the fields of genetic engineering, synthetic biology, chemical biology, xenobiology, and directed evolution.

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