Publications

Articles (*corresponding author)

Zhong Z, Wong BG, Ravikumar A, Arzumanyan GA, *Khalil AS, *Liu CC. Automated Continuous Evolution of Proteins in vivo. ACS Synthetic Biology, In Press (2020).

Loveless TB, Grotts JH, Schechter MW, Forouzmand E, Carlson CK, Agahi BS, Liang G, Ficht M, Liu B, Xie X, *Liu CC. DNA Writing at a Single Genomic Site Enables Lineage Tracing and Analog Recording in Mammalian Cells. BioRxiv, Preprint, 639120 (2019). In Revision.

*Liu CC. A New Path to Tyrosine Sulfation. Nature Chemical Biology, 16, 365-366 (2020).

Wellner A, Ravikumar A, *Liu CC. Continuous Evolution of Proteins in vivo. In H. Zhao (Ed.), Protein Engineering. Wiley-VCH, Accepted (2019).

Javanpour AA, *Liu CC. Genetic Compatibility and Extensibility of Orthogonal Replication. ACS Synthetic Biology, 8, 1249-1256 (2019).

*Loveless TB, *Liu CC. Viewpoint: Synthetic Epigenetics to Engineer Regulation. Biochemistry, 58, 1558-1559 (2019).

Zhong Z, *Liu CC. Probing Pathways of Adaptation with Continuous Evolution. Current Opinion in Systems Biology, 14, 18-24 (2019).

Zhong Z, Ravikumar A, *Liu CC. Tunable Expression Systems for Orthogonal DNA Replication. ACS Synthetic Biology, 7, 2930-2934 (2018).

Ravikumar A, Arzumanyan GA, Obadi MKA, Javanpour AA, *Liu CC. Scalable, Continuous Evolution of Genes at Mutation Rates Above Genomic Error Thresholds. Cell, 175, 1946-1957 (2018).

Arzumanyan GA, Gabriel KN, Ravikumar A, Javanpour AA, *Liu CC. Mutually Orthogonal DNA Replication Systems in vivo. ACS Synthetic Biology, 7, 1722-1729 (2018).

Li X, Hitomi J, *Liu CC. Characterization of a Sulfated Anti-HIV Antibody using an Expanded Genetic Code. Biochemistry, 57, 2903-2907 (2018).

Li X, *Liu CC. Site-Specific Incorporation of Sulfotyrosine Using an Expanded Genetic Code. Methods Molecular Biology, 1728, 191-200 (2018).

*Liu CC, *Jewett MC, *Chin JW, *Voigt CA. Toward an Orthogonal Central Dogma. Nature Chemical Biology, 14, 103-106 (2018).

Schwessinger B, Li X, Ellinghaus TL,…*Liu CC, *Ronald PC. A Second-Generation Expression System for Tyrosine-Sulfated Proteins and its Application in Crop Protection. Integrative Biology, 8, 542-545 (2016).

Pruitt R et al. (29 authors total). The Rice Immune Receptor XA21 Recognizes a Tyrosine-Sulfated Protein from a Gram-Negative Bacterium. Science Advances, 1, e1500245 (2015).

Ravikumar A, *Liu CC. Biocontainment through Reengineered Genetic Codes. ChemBioChem, 16, 1149-1151 (2015).

Li X, *Liu CC. Biological Applications of Expanded Genetic Codes. ChemBioChem, 15, 2335-2341 (2014).

Ravikumar A, Arrieta A, *Liu CC. An Orthogonal DNA Replication System in Yeast. Nature Chemical Biology, 10, 175-177 (2014).

Chen M, Wang L, Liu CC, *Nie Q. Noise Attenuation in the ON and OFF States of Biological Switches. ACS Synthetic Biology, 2, 587-593 (2013).

Guimares JC, Liu CC, *Arkin AP. From Biological Parts to Circuit Design. In H. Zhao (Ed.), Synthetic Biology (pp. 63-77). London: Academic Press (2013).

Liu CC, Qi L, Lucks JB, Segall-Shapiro TH, Wang D, Mutalik VK, *Arkin AP. An Adaptor from Translational to Transcriptional Control Enables Predictable Assembly of Complex Regulation. Nature Methods, 9, 1088-1094 (2012).

Qi L, Lucks JB, Liu CC, Mutalik VK, *Arkin AP. Engineering Naturally Occurring Trans-Acting Non-Coding RNAs to Sense Cellular Signals. Nucleic Acids Research, 40, 5775-5786 (2012).

*Liu CC, Qi L, Yanofsky C, *Arkin AP. Regulation of Transcription by Unnatural Amino Acids. Nature Biotechnology, 29, 164-168 (2011).

*Liu CC, *Arkin AP. The Case for RNA. Science, 330, 1185-1186 (2010).

*Liu CC, *Schultz PG. Adding New Chemistries to the Genetic Code. Annual Reviews of Biochemistry, 70, 413-444 (2010).

Liu CC, Cellitti SE, Geierstanger BH, *Schultz PG. Efficient Expression of Tyrosine-Sulfated Proteins in E. coli using an Expanded Genetic Code. Nature Protocols, 4, 1784-1789 (2009).

Liu CC, Choe H, Farzan M, Smider VV, *Schultz PG. Mutagenesis and Evolution of Sulfated Antibodies using an Expanded Genetic Code. Biochemistry, 48, 8891-8898 (2009).

Mills JH, Lee HS, Liu CC, Wang J, *Schultz PG. A Genetically Encoded Direct Sensor of Antibody-Antigen Interactions. Chembiochem, 10, 2162-2164 (2009).

Liu CC, Mack AV, Brustad E, Mills JH, Groff D, *Smider VV, *Schultz PG. Evolution of Proteins with Genetically Encoded “Chemical Warheads”. Journal of the American Chemical Society, 131, 9616-9617 (2009).

Liu CC, Mack AV, Tsao M, Mills JH, Lee H, Choe H, Farzan M, *Schultz PG, *Smider VV. Protein Evolution with an Expanded Genetic Code. Proceedings of the National Academy of Sciences, 105, 17688-17693 (2008).

Liu CC, Brustad E, *Liu W, *Schultz PG. Crystal Structure of a Biosynthetic Sulfo-hirudin Complexed to Thrombin. Journal of the American Chemical Society, 129, 10648-10649 (2007).

*Liu CC, *Schultz PG. Recombinant Expression of Selectively Sulfated Proteins in E. coli. Nature Biotechnology, 24, 1436-1440 (2006).

Andreana PR, Liu CC, *Schreiber SL. Stereochemical Control of the Passerini Reaction. Organic Letters, 6, 4231-4233 (2004).